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Unión Médica analiza enfermedad inflamatoria intestinal

La enfermedad inflamatoria crónica intestinal en los últimos años en nuestro país ha ido en aumento, por lo que la clínica Unión Médica y su departamento de gastroenterología, a fin de crear conciencia de la enfermedad, celebró un encuentro para analizar la problemática. La doctora Verónica Lockward, responsable de la actividad dijo que la iniciativa se inscribe dentro de las preocupaciones de ese centro de salud por los pacientes, sostuvieron dicha reunión en la que participaron el personal médico y de apoyo. Además de Lockward participaron los doctores Emerson Fernández, coordinador del departamento de gastroenterología, Miguelina Santos, subcoordinadora, Leydi Ureña Médico residente de tercer año, Méndez nutriólogo clínico, Javiela Tejada, hematóloga, contando además con la presencia de la directora médico del centro, doctora María de León Verónica Lockward explicó que esta enfermedad afecta el tracto gastrointestinal como su nombre lo indica, es un proceso inflamatorio crónico de origen autoinmune que incluye tres entidades clínicas conocidas como colitis ulcerativa, enfermedad de crohn y colitis indeterminadas. “Esta clasificación la definimos los gastroenterólogos según criterios clínicos, radiológicos, endoscópicos”, expresó. Manifestó que el tipo colitis ulcerativa afecta la mucosa de colon y su extensión es variable, en cambio la enfermedad de cron puede afectar cualquier área del tracto gastrointestinal desde la boca hasta el ano y todas las capas del mismo ósea, de afectación transmural. COMO AFECTA: La especialista destacó que la enfermedad inflamatoria crónica del intestino se puede presentar a cualquier edad, aunque es más frecuente en la segunda y tercera década de la vida. Dijo que en el caso de la enfermedad de cron es más frecuente en varones, mientras que la colitis ulcerosa es igual para ambos sexos. En la etiología de esta entidad existe un factor genético importante, se han descubiertos genes que están asociados a la misma como el gen NOD2 y Card 15, entre otros, los factores ambientales de la dieta, vivir en zonas urbanas e industrializadas. También el tabaco con un efecto protector para colitis ulcerosa y agravada en crohn mas una respuesta inmune alterada en estos pacientes, hacen que todos estos factores se unan y den inicio a la enfermedad. Dijo que clínicamente, se manifiesta en la colitis ulcerativa por diarrea liquida, sanguinolenta, asociada a urgencia y tenesmo, dolor abdominal tipo cólico, pérdida de peso, fiebre, puede presentar complicaciones que son incluso fatales como la colitis fulminante, el megacolon toxico y puede evolucionar sino es tratada adecuadamente en cáncer de colon. En el caso de la enfermedad de crohn las manifestaciones clínicas son básicamente dolor abdominal que suele estar localizado en el cuadrante inferior derecho del abdomen o en la zona alrededor del ombligo. “En algunos casos se presentan sensación de una masa palpable en la misma área descrita, diarrea o estreñimiento, retraso del crecimiento, al inicio de la enfermedad el paciente puede tener anorexia ósea pérdida del apetito, falta de ánimo, fiebre intermitente”, precisó. COMPLICACIONES La doctora Verónica Lockward señaló que entre las complicaciones de la enfermedad de cron, están el desarrollo de zonas de estenosis intestinales, fistulas y abscesos como las más frecuentes. El paciente con enfermedad de crohn suele presentar manifestaciones articulares como artritis, sacroileitis, manifestaciones en piel, como el pioderma gangreso. “Incluso, los paciente tienen un estado de hipercogubilidad por lo que incluso pueden llegar a presentar tombosis venosas y subsecuentemente tromboembolismo pulmonar que es una complicación grave de la enfermedad”, subraya. Afirman que el diagnostico de la misma necesita de la interrelación entre la clínica, pruebas de carácter inflamatorio como PCR calprotectina fecal, eritrosedimentacion, el 50% de los paciente suelen presentar anemia, están las pruebas de carácter inmunológico como el ANCA y ASCA. El estudio del tracto gastrointestinal a través de estudios endoscópicos altos y bajos y otros complementarios como el enema de bario, tomografías de abdomen, resonancia abdominal, videocapsula. TRATAMIENTO De acuerdo a la especialista el tratamiento de las misma está dirigido a disminuir los brotes, procurar que el paciente entre en estado de remisión y pueda tener calidad de vida, que el mismo se convierta en un ser socialmente activo, que la enfermedad deje de ser una limitante para el desarrollo de una vida plena. En ese sentido dijo que existen muchas terapias que utilizamos los gastroenterólogos dependiendo del grado de actividad de la enfermedad, como los aminosalisilatos, mesalamina, esteroides, inmunomoduladores como azatriopina, metrotexate. Además los más recientes los biológicos que tienen un beneficio potencial en los mismos ya que actúan directamente inactivando al factor de necrosis tumoral que es una de los factores más recientemente descubiertos que juegan u papel principal en el desarrollo de la enfermedad. Muchos pacientes necesitan a parte del manejo medico el manejo quirúrgico por las complicaciones inherentes de la enfermedad. Es importante que el país se tome en cuenta esta enfermedad, porque si la misma no es tratada se convierte en incapacitante para el paciente, que los médicos tomen conciencia de la misma y de sus implicaciones clínicas y que el paciente este informado y que pueda participar en la toma de decisiones junto al médico para un mejor manejo de su patología.

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